Research Interests
"hybrid theranostic platforms with different anisotropic plasmonic nanoparticles and their application in cancer therapy""""""
Expertise
Alexandru Holca is a fourth-year PhD student at the Faculty of Physics. He obtained both his bachelor's and master's degrees from the Faculty of Chemistry and Chemical Engineering, specializing in Organic Compounds Chemistry and Engineering. His research interests focus on the synthesis of anisotropic gold nanoparticles and their characterization using spectroscopic techniques such as UV–Vis and IR spectroscopy. In addition, his work involves the study of graphene oxide and reduced graphene oxide. The main topic of his PhD research is photothermal therapy, where he investigates the use of gold nanorods together with graphene oxide and reduced graphene oxide for in vitro studies.
International visibility
- Co-author of 4 ISI articles, two as main author
- 4 international conference participation
- Key member in 2 research projects
Most Relevant Publications
Recent advances in gold nanoparticle-graphene hybrid nanoplatforms with visible to near-infrared response for photodynamic and photothermal therapy and bioimaging, A. Holca, V. Cucuiet, S. Astilean, M. Lamy de la Chapelle, M. Focsan, RSC Advances, 2025
LED-Activated NIR-II Gold Nanorods for Photothermal Therapy of 3D Melanoma Spheroids, A. Holca, R. Borlan, A. Campu, S. Dragan, M. Muntean, A.-M. Craciun, A. Sesarman, M. Banciu, S. Astilean, M. Lamy de la Chapelle, M. Focsan
Plasmon-Driven Catalytic Inhibition of pATP Oxidation as a Mechanism for Indirect Fe²⁺ Detection on a SERS-Active Platform, A.-M. Hada, M.-M. Moruz, A. Holca, S. Astilean, M. Lamy de la Chapelle, M. Focsan
Photophysical Properties of 1,3-Diphenylisobenzofuran as a Sensitizer and Its Reaction with O2, S. Stan, J. P. P. Ramalho, A. Holca, V. Chis