Raluca Lăpușan-Borlan


Research Interests

Raluca is a PhD researcher with an ongoing interest focused on two complementary topics: The development and characterization of organic nanoparticles loaded with different classes of near infrared fluorophores, as contrast agents for real time image-guided cancer surgery; Thus, Raluca's second topic of interest is the biofunctionalization and in vitro investigation of the synthesized nanoparticles for specific targeting of ovarian cancer cells.


  • Synthesis, optimization and spectroscopic characterisation of protein-based nanoparticles 
  • Nanoparticles biofunctionalization for targeted delivery and fluorescence-guided imaging

International visibility

  • Main author of 4 ISI article and 2 international conference participation as main presenter with poster

For more information, please consult:  

ORCID iD: 0000-0003-3581-3020 - orcid.org

BrainMap ID: U-1900-061V-8864 - brainmap.ro

Google Scholar: scholar.google.com

Email: raluca.borlan@ubbcluj.ro

Phone: +40 264 454554/ int 117

Most Relevant Publications

Antioxidant Activity Evaluation and Assessment of the Binding Affinity to HSA of a New Catechol Hydrazinyl-Thiazole Derivative, M Mic, A Pîrnău, C G Floare, R Borlan, M Focsan, O Oniga, M Bogdan, L Vlase, I Oniga, G Marc, Antioxidants 11 (7), 1245 (2022)

Antibody Functionalized Theranostic Protein Nanoparticles for Synergistic Deep Red Fluorescence Imaging and Multimodal Therapy of Ovarian Cancer, R Borlan, M Focsan, M Perde-Schrepler, O Soritau, A Campu, L Gaina, E Pall, B Pop, O Baldasici, C Gherman, D Stoia, D Maniu and S Astilean, Biomaterials Science (2021)

Fluorescent phthalocyanine-encapsulated bovine serum albumin nanoparticles: their deployment as therapeutic agents in the NIR region, R Borlan, D Stoia, L Gaina, A Campu, G Marc, M Perde-Schrepler, M Silion, D Maniu, M Focsan and S Astilean; Molecules, 26(15): 4697 (2021)

Interventional NIR Fluorescence Imaging of Cancer: Review on Next Generation of Dye Loaded Protein-Based Nanoparticles for Real-Time Feedback During Cancer Surgery, R Borlan, M Focsan, D Maniu, and S Astilean, International Journal of Nanomedicine, 16: 2147–71 (2021)

Design of Fluorophore Loaded Human Serum Albumin Nanoparticles for Specific Targeting of NIH:OVCAR3 Ovarian Cancer Cells, R. Borlan, A-S. Tatar, O. Sorita, D. Maniu, G. Marc, A. Florea, M. Focsan, S. Astilean, Nanotechnology, 31(31): 315102 (2020).